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• Beyond average: potential for measurement of short telomeres
• Prather AA et al. (2011). "Shorter leukocyte telomere length in midlife women with poor sleep quality." J Aging Res. 2011:721390.
• Wills LP et al. (2011). "Telomeres and telomerase in renal health." J Am Soc Nephrol. Jan;22(1):39-41.
• Donate LE et al. (2011). “Telomeres in cancer and ageing.” Phil. Trans. R. Soc. B 366,76-84.
• Bernardes de Jesus B et al. (2010). “Aging by Telomere Loss Can Be Reversed.” Cell Stem Cell 8(1):3-4.
• Flores I et al. (2008). ”The longest telomeres: a general signature of adult stem cell compartments.” Genes & Development 22(5):654-67.
• Ornish D et al. (2008). “Increased telomerase activity and comprehensive lifestyle changes: a pilot study.” Lancet Oncol. Nov;9(11):1048-57. www.ncbi.nlm.nih.gov/pubmed/18799354
• Pérez - Rivero G et al. (2008). “Telomerase deficiency promotes oxidative stress by reducing catalase activity.” Free Radic. Biol. Med. 45(9):1243-51.
• Canela A et al. (2007). ”High-throughput telomere length quantification by FISH and its application to human population studies.” Proc. Natl. Acad. Sci. 104(13):5300-5.
• Collado M et al. (2007). “Cellular senescence in cancer and aging.” Cell 130(2):223-233.
• García CK et al. (2007). “Human diseases of telomerase dysfunction: insights into tissue aging.” Nucleic. Acid Res. 35(22):7406-7416.
• Valdes AM et al. (2005). “Obesity, cigarette smoking and telomere length in women.” Lancet 366(9486):662-664.
• Franco S et al. (2004). “Telomere dynamics in Fancg-deficient mouse and human cells.” Blood 104(13):3927-35.
• Collins K et al. (2002). “Telomerase in the human organism.” Oncogene 21(4):564-579.
• Von Zglinicki T (2002). “Oxidative stress shortens telomeres.” Trends Biochem. Sci. 27(7):339-344.
• Wiemann SU et al. (2002). “Hepatocyte telomere shortening and senescence are general markers of human liver cirrhosis.” FASEB J. 16(9):935-942.
• Hemann MT et al. (2001). “The shortest telomere, not average telomere length is critical for cell viability and chromosome stability.” Cell 107(1):67-77.
• Samper E et al. (2001). “Restoration of telomerase activity rescues chromosomal instability and premature aging in Terc–/– mice with short telomeres.” EMBO Reps. 2(9):800-807.
• González – Suárez E et al. (2000). “Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis” Nat. Genet. 26(1):114-7.
• Blasco MA et al. (1997). “Telomere shortening and tumor formation by mouse cells lacking telomerase RNA.” Cell 91(1):25-34.
• Allsopp RC et al. (1992). “Telomere Length predicts replicative capacity of human fibroblasts.” Proc. Natl. Acad. Sci. 89(21):10114-10118.

Vieillissement

• Bernardes de Jesus B et al. (2012). “Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer.” EMBO Mol Med. May 15. doi: 10.1002/emmm.201200245
• Njajou OT et al. (2011). "Shorter telomeres are associated with obesity and weight gain in the elderly." Int J Obes (Lond). Oct 18. doi: 10.1038/ijo.2011.196.
• Lin J et al. (2011). "Telomeres and lifestyle factors: Roles in cellular aging." Mutat Res. Aug 22.
• Buckingham EM et al. (2011). "The role of telomeres in the ageing of human skin." Exp Dermatol. Apr;20(4):297-302. doi: 10.1111/j.1600-0625.2010.01242.x.
• Chen W et al. (2011). "Longitudinal versus cross-sectional evaluations of leukocyte telomere length dynamics: age-dependent telomere shortening is the rule." J Gerontol A Biol Sci Med Sci. Mar;66(3):312-9.
• Sanders JL et al. (2011). "Leukocyte Telomere Length Is Associated With Noninvasively Measured Age-Related Disease: The Cardiovascular Health Study." J Gerontol A Biol Sci Med Sci. Sep 20.
• Puterman E et al. (2010). “The power of exercise: buffering the effect of chronic stress on telomere length.” PLoS One. 5(5):e10837.
• Epel ES et al. (2009). “The rate of leukocyte telomere shortening predicts mortality from cardiovascular disease in elderly men.” Aging 1(1):81-88.
• Tomas-Loba A et al. (2008). “Telomerase reverse transcriptase delays aging in cancer-resistant mice.” Cell 135(4):609-622.
• Blasco MA et al. (2007). “Telomere length, stem cells and aging.” Nat. Chem. Biol. 3(10):640-649.
• Effros RB (2007). “Telomerase induction in T-Cells: a cure for aging and disease?” Exp. Gerontol. 42(5):416-420.
• Harris SE et al. (2006). “The association between telomere length physical health, cognitive aging and mortality in non-demented older people.” Neurosci. Lett. 406(3):260-264.
• Blasco MA et al. (2005). “Telomeres and human disease: ageing, cancer and beyond.” Nat. Rev. Genet. 6(8):611-622.
• Von Zglinikci T et al. (2005). “Telomeres as biomarkers for ageing and age-related diseases.” Curr. Mol. Med. 5(2):197-203.
• Epel ES et al. (2004). “Accelerated telomere shortening in response to life stress.” Proc. Natl. Acad. Sci. 101(49):17312-17315.
• Vulliamy T et al. (2004). “Disease anticipation is associated with progressive telomere shortening in families with dyskeratosis congenita due to mutations in TERC.” Nat. Genet. 36(5):447-449.
• Cawthon M et al. (2003). “Association between telomere length in blood and mortality in people aged 60 years or older.” Lancet 361(9355):393-395.
• Bodnar AG et al. (1998). “Extension of life-span by introduction of telomerase into normal human cells.” Science 279 (5349):349-352.
• Iwama H et al. (1998). “Telomeric Length and telomerase activity vary with age in peripheral blood cells obtained from normal individuals.” Hum. Genet. 102(4):397-402.
• Harley CB et al. (1990). “Telomeres shorten during ageing of human fibroblasts.” Nature 345(6274):458-460.

Système cardiovasculaire

• Olivieri F et al. (2011). "Telomere/Telomerase System: A New Target of Statins Pleiotropic Effect?" Curr Vasc Pharmacol. Oct 21.
• Aviv A (2011). "Genetics of leukocyte telomere length and its role in atherosclerosis." Mutat Res. May 8.
• Maeda T et al. (2011). "The correlation between the clinical laboratory data and the telomere length in peripheral blood leukocytes of Japanese female patients with hypertension." J Nutr Health Aging. Mar;15(3):240-4.
• Nzietchueng R et al. (2011). "Telomere length in vascular tissues from patients with atherosclerotic disease." J Nutr Health Aging. Feb;15(2):153-6
• Fitzpatrick AL et al. (2011). "Leukocyte telomere length and mortality in the Cardiovascular Health Study." J Gerontol A Biol Sci Med Sci. Apr;66(4):421-9.
• De Meyer T et al. (2011). "Telomere length and cardiovascular aging: the means to the ends?" Ageing Res Rev. Apr;10(2):297-303.
• Wang YY et al. (2011). "Association of shorter mean telomere length with large artery stiffness in patients with coronary heart disease." Aging Male. Mar;14(1):27-32.
• Saliques S et al. (2011). "Circulating leukocyte telomere length and oxidative stress: A new target for statin therapy." Atherosclerosis. Sep 16.
• Hoffmann J et al. (2011). "Telomere length in cardiovascular disease: new challenges in measuring this marker of cardiovascular aging." Future Cardiol. Sep;7(5):693-707.
• Wong LS et al. (2011). "Telomere length of circulating leukocyte subpopulations and buccal cells in patients with ischemic heart failure and their offspring." PLoS One. 6(8):e23118.
• Willeit P et al. (2010). “Cellular aging reflected by leukocyte telomere length predicts advanced atherosclerosis and cardiovascular disease risk.” Arterioscler Thromb Vasc Biol. Aug;30(8):1649-56.
• Chen W et al. (2009). “Leukocyte telomere length is associated with HDL cholesterol levels: The Bogalusa heart study.” Atherosclerosis. Aug;205(2):620-5.
• Diez Roux A V et al. (2009). “Race/ethnicity and telomere length in the Multi-Ethnic Study of Atherosclerosis.“ Aging Cell. Jun;8(3):251-7.
• Kaplan R C et al. (2009). “Insulin-like growth factors and leukocyte telomere length: the cardiovascular health study.” J Gerontol A Biol Sci Med Sci. Nov;64(11):1103-6.
• Zee R Y et al. (2009). “Association of shorter mean telomere length with risk of incident myocardial infarction: A prospective, nested case-control approach.” Clin Chim Acta. May;403(1-2):139-41.
• Farzaneh-Far R et al. (2008). “Prognostic value of leukocyte telomere length in patients with stable coronary artery disease: data from the Heart and Soul Study.” Arterioscler Thromb Vasc Biol. Jul;28(7):1379-84.
• Kimura M et al. (2008). “Telomere length and mortality: a study of leukocytes in elderly Danish twins.” Am. J. Epidemiol. 167(7):799-806.
• Samani NJ et al. (2008). “Biological ageing and cardiovascular disease.” Heart 94(5):537-539.
• Vasan R S et al. (2008). “Association of leukocyte telomere length with circulating biomarkers of the renin-angiotensin-aldosterone system: the Framingham Heart Study. “ Circulation. Mar 4;117(9):1138-44.
• Bakaysa SL et al. (2007). “Telomere length predicts survival independent of genetic influences.” Aging Cell 6(6):769-774.
• Bekaert S et al. (2007). “Telomere length and cardiovascular risk factors in a middle-aged population free of overt cardiovascular disease.” Aging Cell. Oct;6(5):639-47.
• Brouilette SW et al. (2007). “Telomere length, risk of coronary heart disease, and statin treatment in the West of Scotland Primary Prevention Study: a nested case-control study.” Lancet. Jan 13;369(9556):107-14.
• Van der Harst P et al. (2007). “Telomere length of circulating leukocytes is decreased in patients with chronic heart failure.” J Am Coll Cardiol. Apr 3;49(13):1459-64.
• Demissie S et al. (2006). “Insulin resistance, oxidativestress, hypertension, and leukocyte telomere length in men from the Framingham Heart Study.” Aging Cell 5(4):325-330.
• Pérez-Rivero G et al. (2006). “Mice deficient in telomerase activity develop hypertension because of an excess of endothelin production.” Circulation 114(4):309-317.
• Benetos A et al. (2004). “Short telomeres are associated with increased carotid atherosclerosis in hypertensive subjects.” Hypertension. Feb;43(2):182-5.
• Ogami M et al. (2004). “Telomere shortening in human coronary artery diseases.” Arterioscler. Thromb. Vasc. Biol. 24(3):546-550.
• Brouilette S et al. (2003). “White cell telomere length and risk of premature myocardial infarction.” Arterioscler. Thromb. Vasc. Biol. 23(5):842-846.
• Leri A et al. (2003). “Ablation of telomerase and telomere loss leads to cardiac dilatation and heart failure associated with p53 upregulation.“ EMBO J. 22(1):131-139.
• Benetos A et al. (2001). “Telomere length as an indicator of biological aging: the gender effect and relations with pulse pressure and pulse wave velocity.” Hypertension 37 (2 part 2):381-385.
• Samani NJ et al. (2001). “Telomere shortening in atherosclerosis.” Lancet 358(9280):472-473.
• Jeanclos E et al. (2000). “Telomere length inversely correlates with pulse pressure and is highly familiar.” Hypertension 36(2):195-200.

Système nerveux central

• Kljajevic V. (2011). "From cell to cognition: can changes in telomere length indicate patterns of cognitive aging?" Clin Sci (Lond). Oct 1;121(7):313-4.
• Watfa G et al. (2011). "Study of telomere length and different markers of oxidative stress in patients with Parkinson's disease." J Nutr Health Aging. Apr;15(4):277-81.
• Elvsåshagen T et al. (2011). "The load of short telomeres is increased and associated with lifetime number of depressive episodes in bipolar II disorder." J Affect Disord. Dec;135(1-3):43-50.
• Eerola J et al. (2010). “No evidence for shorter leukocyte telomere length in Parkinson's disease patients.” J Gerontol A Biol Sci Med Sci. 2010 Nov;65(11):1181-4.
• Lin J et al. (2010). “Endogenous estrogen exposure is associated with the telomere maintenance in postmenopausal women at risk for cognitive decline.” Brain Res. Oct 18.
• Valdes A M et al. (2010). “Leukocyte telomere length is associated with cognitive performance in healthy women.” Neurobiol Aging. Jun;31(6):986-92.
• Zekry D et al. (2010). “Telomere length and ApoE polymorphism in mild cognitive impairment, degenerative and vascular dementia.” J Neurol Sci. Aug 13.
• Guan JZ et al. (2008). “A percentage analysis of the telomere length in Parkinson's disease patients.” JGerontol A Biol Sci Med Sci. May;63(5):467-73.
• Wang H et al. (2008). “Telomere length and risk of Parkinson's disease.” Mov Disord. 2008 Jan 30;23(2):302-5.
• Franco S et al. (2006). “Telomeres and telomerase in Alzheimer's disease: epiphenomena or a new focus for therapeutic strategy?” Alzheimers Dement 2(3):164-168.
• Honig LS et al. (2006). “Shorter telomeres are associated with mortality in those with APOE epsilon4 and dementia.” Ann. Neurol. 60(2):181-187.
• Simon NM et al. (2006). “Telomere shortening and mood disorders: preliminary support for a chronic stress model of accelerated aging. “ Biol. Psychiatry 60(5):432-435
• Harris SE et al. (2006). “The association between telomere length, physical health, cognitive aging and mortality in non-demented older people.” Neurosci. Lett. 406(3):260-264.
• Panossian LA et al. (2003). “Telomere shortening in T cells correlates with Alzheimer´s disease status.” Neurobiol. Aging 24(1):77-84.

Diabète

• Testa R et al. (2011). "Leukocyte telomere length is associated with complications of Type 2 diabetes mellitus." Diabet Med. Nov;28(11):1388-1394. doi: 10.1111/j.1464-5491.2011.03370.x.
• Zee RY et al. (2011). "Genetic variants of 11 telomere-pathway gene loci and the risk of incident type 2 diabetes mellitus: the Women's Genome Health Study." Atherosclerosis. Sep;218(1):144-6.
• Murillo-Ortiz B et al. (2011). "Telomere length and type 2 diabetes in males, a premature aging syndrome." Aging Male. Aug 9.
• Xiao F et al. (2011). "Telomere dysfunction-related serological markers are associated with type 2 diabetes." Diabetes Care. Oct;34(10):2273-8.
• Guo N et al. (2011). “Short telomeres compromise β-cell signaling and survival. PLoS One.” Mar 10;6(3):e17858.
• Astrup AS et al. (2010). “Telomere length predicts all-cause mortality in patients with type 1 diabetes.“ Diabetologia. Jan;53(1):45-8.
• Kuhlow D et al. (2010). “Telomerase deficiency impairs glucose metabolism and insulin secretion.“ Aging (Albany NY). Oct;2(10):650-8.
• Zee RY et al. (2010). “Mean leukocyte telomere length shortening and type 2 diabetes mellitus: a case-control study.” Transl Res. Apr;155(4):166-9.
• Adaikalakoteswari A et al. (2007). “Association of telomere shortening with impaired glucose tolerance and diabetic macroangiopathy.” Atherosclerosis. Nov;195(1):83-9.
• Sampson M J et al. (2006). “Monocyte telomere shortening and oxidative DNA damage in type 2 diabetes.” Diabetes Care. Feb;29(2):283-9.

Alimentation/obésité

• Paul L. et al. (2011). "Diet, nutrition and telomere length." J Nutr Biochem. Oct;22(10):895-901. doi: 10.1016/j.jnutbio.2010.12.001.
• Farzaneh-Far R et al. (2010). “Association of marine omega-3 fatty acid levels with telomeric aging in patients with coronary heart disease.” JAMA. Jan 20;303(3):250-7.
• Lee M et al. (2010). “Inverse association between adiposity and telomere length: The fels longitudinal study.” Am J Hum Biol. Nov 15.
• Nordfjall K et al. (2010). “Increased abdominal obesity, adverse psychosocial factors and shorter telomere length in subjects reporting early ageing; the MONICA Northern Sweden Study.” Scand J Public Health;5(1):e8612.
• Kim S et al. (2009). “Obesity and weight gain in adulthood and telomere length.” Cancer Epidemiol Biomarkers Prev. Mar;18(3):816-20.
• Xu Q et al. (2009). “Multivitamin use and telomere length in women.” Am J Clin Nutr. 2009 Jun;89(6):1857-63.
• Zannolli R et al. (2008). “Telomere length and obesity.” Acta Paediatr. Jul;97(7):952-4.
• Richards JB et al. (2007). “Higher serum vitamin D concentrations are associated with longer leukocyte telomere length in women.” Am J Clin Nutr. Nov;86(5):1420-5.

Immunologie

• Harley CB et al. (2011). “A Natural Product Telomerase Activator As Part of a Health Maintenance Program.” Rejuvenation. Res. 14(1):45-56.
• Hoare M et al. (2010). “CD4+ T-lymphocyte telomere length is related to fibrosis stage, clinical outcome and treatment response in chronic hepatitis C virus infection.” J Hepatol. Aug;53(2):252-60.
• Scheinberg P et al. (2010). “Association of telomere length of peripheral blood leukocytes with hematopoietic relapse, malignant transformation, and survival in severe aplastic anemia.” JAMA. 2010;304(12): 1358-1364.
• Gharagozloo M et al. (2009). “Premature senescence of T lymphocytes from patients with beta-thalassemia major.” Immunol Lett. Jan 29;122(1):84-8.
• Fauce SR et al. (2008). “Telomerase-based pharmacologic enhancement of antiviral function of human CD8+ T lymphocytes.” J. Immunol. 181(10):7400-7406.
• Martín Ruiz C et al. (2006). “Stroke mortality, dementia and cognitive decline.” Ann. Neurol. 60(2):174-180.
• Dagarag M et al. (2004). “Genetic Manipulation of telomerase in HIV-specific CD8+ T Cells: enhanced antiviral functions accompany the increased proliferative potential and telomere length stabilization.” J. Inmmunol. 173(10):6303-6311.

Infertilité

• Keefe DL et al. (2006). “The telomere theory of reproductive senescence in women.” Curr. Opin. Obstet. Gynecol. 18(3):280-285.
• Keefe DL et al. (2005). “Telomere length predicts embryo fragmentation after in vitro fertilization in women-toward a telomere theory of reproductive aging in women.” Am. J. Obstet. Gynecol. 192(4):1256-1260; discussion 1260-1251.
• Okuda K et al. (2002). “Telomere length in the new born.” Pediatr. Res. 52(3):377-381.
• Liu L et al. (2002). “Requirement of functional telomeres for metaphase chromosome alignements and integrity of meiotic spindles.” EMBO Rep. 3(3):230-234.
• Liu L et al. (2002). “Oxidative Stress Contributes to Arsenic-Induced Telomere Attrition, Chromosome Instability and Apoptosis.” EMBO Rep. 3(3):230-234.
• Wright DL et al. (2001). “Characterization of telomerase activity in the human oocyte and preimplantation embryo.” Mol. Hum. Reprod. 7(10):947-955.

Oncologie

• Hofmann JN et al. (2011). "Risk of renal cell carcinoma in relation to blood telomere length in a population-based case-control study." Br J Cancer. Oct 27. doi: 10.1038/bjc.2011.444
• Calado RT et al. (2011). "Short telomeres result in chromosomal instability in hematopoietic cells and precede malignant evolution in human aplastic anemia." Leukemia. Oct 18. doi: 10.1038/leu.2011.272.
• Kim S et al. (2011). "Telomere length in peripheral blood and breast cancer risk in a prospective case-cohort analysis: results from the Sister Study." Cancer Causes Control. Jul;22(7):1061-6.
• Rollison DE et al. (2011). "Telomere length in myelodysplastic syndromes." Leuk Lymphoma. 2011 Aug;52(8):1528-36.
• Mirabello L et al. (2011). "Telomere length and variation in telomere biology genes in individuals with osteosarcoma." Int J Mol Epidemiol Genet. Jan 1;2(1):19-29.
• Wentzensen IM et al. (2011). "The association of telomere length and cancer: a meta-analysis." Cancer Epidemiol Biomarkers Prev. Jun;20(6):1238-50.
• Heaphy CM et al. (2011). "The potential utility of telomere-related markers for cancer diagnosis." J Cell Mol Med. Jun;15(6):1227-38. doi: 10.1111/j.1582-4934.2011.01284.x.
• Folini M et al. (2011). "Telomeres as targets for anticancer therapies." Expert Opin Ther Targets. May;15(5):579-93.
• Sellmann L et al. (2011). "Telomeres and prognosis in patients with chronic lymphocytic leukaemia." Int J Hematol. Jan;93(1):74-82.
• Donate LE et al. (2011). "Telomeres in cancer and ageing." Philos Trans R Soc Lond B Biol Sci. Jan 12;366(1561):76-84.
• Valls C et al. (2011). "Telomere length is a prognostic factor for overall survival in colorectal cancer." Colorectal Dis. Nov;13(11):1265-72. doi: 10.1111/j.1463-1318.2010.02433.x.
• Kheirollahi M et al. (2011). "Alterations of telomere length in human brain tumors." Med Oncol. Sep;28(3):864-70.
• Franks I. (2011). "Colorectal cancer: Telomere length and risk of CRC." Nat Rev Gastroenterol Hepatol. Sep 2;8(9):475. doi: 10.1038/nrgastro.2011.136.
• Capezzone M et al. (2011). "Telomere Length in Neoplastic and Nonneoplastic Tissues of Patients with Familial and Sporadic Papillary Thyroid Cancer." J Clin Endocrinol Metab. Aug 24.
• Surtees PG et al. (2011). "Life Stress, Emotional Health, and Mean Telomere Length in the European Prospective Investigation into Cancer (EPIC)-Norfolk Population Study." J Gerontol A Biol Sci Med Sci. Nov;66(11):1152-62.
• de Jesús BB et al. (2011). “The telomerase activator TA-65 elongates short telomeres and increases health span of adult ⁄old mice without increasing cancer incidence”. Aging Cell. doi: 10.1111/j.1474-9726.2011.00700.x.
• Martínez P et al. (2011). “Telomeric and extra-telomeric roles for telomerase and the telomere-binding proteins.” Nature Reviews Cancer 11(3):161-176.
• Bautista CV et al. (2010). “Telomere length is a prognostic factor for overall survival in colorectal cancer.” Colorectal Dis. Sep 27;doi:10.1111.
• Lee I et al. (2010). “Mean leukocyte telomere length and risk of incident colorectal carcinoma in women: a prospective, nested case-control study.” Clin. Chem. Lab. Med. 48(2):259-262.
• Pooley KA et al. (2010). “Telomere length in prospective and retrospective cancer case-control studies.” Cancer Res. 70 (8):3170-3176.
• Prescott J et al. (2010). “Telomere length and genetic analyses in population-based studies of endometrial cancer risk.” Cancer. Sep 22;304(12):1358-64.
• Willeit P et al. (2010). “Telomere length and risk of incident cancer and cancer mortality. JAMA.” 2010 Jul 7;304(1):69-75.
• De Vivo I et al. (2009). “A prospective study of relative telomere length and postmenopausal breast cancer risk.” Cancer Epidemiol. Biomarkers Prev. 18(4):1152-1156.
• Hosgood H D 3rd et al. (2009). “Genetic variation in telomere maintenance genes, telomere length, and lung cancer susceptibility.” Lung Cancer. Nov;66(2):157-61.
• Rossi D et al. (2009). “Telomere length is an independent predictor of survival, treatment requirement and Richter's syndrome transformation in chronic lymphocytic leukemia Leukemia.” Jun;23(6):1062-72.
• Svenson U et al. (2009). “Telomere length in peripheral blood predicts survival in clear cell renal cell carcinoma.” Cancer Res. Apr 1;69(7):2896-901.
• Zee RYL et al. (2009). “Mean telomere length and risk of incident colorectal carcinoma: a prospective, nested case-control approach.” Cancer Epidemiol. Biomarkers Prev. 18(8):7423-7428.
• Deng Y et al. (2008). “Telomere dysfunction and tumour suppression: the senescence connection.” Nat. Rev. Cancer 8(6):450-458.
• Harley CB (2008). “Telomerase and cancer therapeutics.” Nat. Rev. Cancer 8(3):167-179.
• Lotan Y et al. (2008). “Screening for bladder cancer: a perspective.” World J. Urol. 26(1):13-18.
• Svenson U et al. (2008). “Breast cancer survival is associated with telomere length in peripheral blood cells.” Cancer Res. 68(10):3618-3623.
• Vera E et al. (2008). “Epigenetic regulation of telomeres in human cancer.” Oncogene 27,6817–6833; doi:10.1038/onc.2008.289.
• Joshua A M et al. (2007). “Telomere attrition in isolated high-grade prostatic intraepithelial neoplasia and surrounding stroma is predictive of prostate cancer.” Neoplasia. Jan;9(1):81-9.
• McGrath M et al. (2007). “Telomere length, cigarette smoking and bladder cancer risk in men and women.” Cancer Epidemiol. Biomarkers Prev. 16(4):815-819.
• Shao L et al. (2007). “Telomere dysfunction in peripheral lymphocytes as a potential predisposition factor for renal cancer.” J Urol. Oct;178(4 Pt 1):1492-6.
• Shen J et al. (2007). “Short telomere length and breast cancer risk: a study in sister sets.” Cancer Res. 67(11):5538-5544.
• Ohali A et al. (2006). “Telomere length is a prognostic factor in neuroblastoma.” Cancer 107(6):1391-1399.
• Shay J et al. (2006). “Telomerase therapeutics for cancer: challenges and new directions.” Nat. Rev. Drug Discov. 5(7):577-584.
• Ulaner GA et al. (2003). “Absence of a telomere maintenance mechanism as a favourable prognostic factor in patients with osteosarcoma.” Cancer Res. 58(18):4168-4172.
• Wu X et al. (2003). “Telomere dysfunction: a potential cancer predisposition factor.” J Natl. Cancer Inst. 95(16):1211-8.
• Rudolph KL et al. (2001). “Telomere dysfunction and evolution of intestinal carcinoma in mice and humans.” Nat. Genet. 28(2):155-159.
• González-Suárez E et al. (2000). “Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis.” Nat Genet. 26:114–117.
• Bachor C et al. (1999). “Telomerase is active in normal gastrointestinal mucosa ns not up-regulated in precancerous lesions.” J Cancer Res. Clin. Oncol. 125(8-9):453-460.
• Takakura M et al. (1998). “Expression of human telomerase subunits and correlation with telomerase activity in cervical cancer.” Cancer Res. 58(7):1558-1561.
• Armanios MY et al. (2007). “Telomerase mutations in families with idiopathic pulmonary fibrosis.” New England Journal of Medicine 356 (13):1317-1326.
• Tsakiri KD et al. (2007). “Adult-onset pulmonary fibrosis caused by mutations in telomerase.” Proc. Natl. Acad. Sci. 104(18):7552-7557.
• Morla M et al. (2006). “Telomere shortening in smokers with and without COPD.” Eur. Respir. J. 27 (3):525-528.
• Broberg K et al. (2005). “Constitutional short telomeres are strong genetic susceptibility markers for bladder cancer.” Carcinogenesis. Feb 22;26( 7):1263-127.

Ostéoporose

• Tang N L et al. (2010). “The effect of telomere length, a marker of biological aging, on bone mineral density in elderly population.” Osteoporos Int. Jan;21(1):89-97.
• Sanders J L et al. (2009). “Leukocyte Telomere Length Is Not Associated With BMD, Osteoporosis, or Fracture in Older Adults: Results From the Health, Aging and Body Composition Study.” J Bone Miner Res. Sep;24(9):1531-6.
• Valdes A M et al. (2007). “Telomere length in leukocytes correlates with bone mineral density and is shorter in women with osteoporosis.” Osteoporos Int. Sep;18(9):1203-10.

Appareil respiratoire

• Amsellem V et al. (2011). "Telomere Dysfunction Causes Sustained Inflammation in Chronic Obstructive Pulmonary Disease." Am J Respir Crit Care Med. Sep 8.
• Noureddine H et al. (2011). "Pulmonary artery smooth muscle cell senescence is a pathogenic mechanism for pulmonary hypertension in chronic lung disease." Circ Res. Aug 19;109(5):543-53.
• Barcelo A et al. (2010). “Telomere shortening in sleep apnea syndrome.” Respir Med. Aug;104(8):1225-9.
• Alder J K et al. (2008). “Short telomeres are a risk factor for idiopathic pulmonary fibrosis.” Proc Natl Acad Sci U S A. Sep 2;105(35):13051-6.

Polyarthrite rhumatoïde

• Harbo M et al. (2012). "The distribution pattern of critically short telomeres in human osteoarthritic knees." Arthritis Res Ther. Jan 18;14(1):R12.
• Fujii H et al. (2009). Telomerase insufficiency in rheumatoid arthritis. Proc Natl Acad Sci U S A. Mar 17;106(11):4360-5.
• Colmegna I et al. (2008). “Defective proliferative capacity and accelerated telomeric loss of hematopoietic progenitor cells in rheumatoid arthritis.” Arthritis Rheum. Apr;58(4):990-1000.
• Steer SE et al. (2007). “Reduced telomere length in rheumatoid arthritis is independent of disease activity and duration. “ Ann Rheum Dis. April;66(4):476–480.

Cellules mères

• Marión RM et al. (2010). “Telomere rejuvenation during nuclear reprogramming.” Curr. Opin. Genet. Dev. 20(2):190-196.
• Flores I et al. (2009). “A p53-Dependent Response Limits Epidermal Stem Cell Functionality and Organismal Size in Mice with Short Telomeres.” PLoS ONE 4(3):e4934. doi:10.1371/journal.pone.0004934.
• Marión RM et al. (2009). “A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity.” Nature 460(7259):1149-53.
• Marión RM et al. (2009). “Telomeres Acquire Embryonic Stem Cell Characteristics in Induced Pluripotent Stem Cells.” Cell Stem Cell 4(2):141-154.
• Flores I et al. (2005). “Effects of Telomerase and Telomere Length on Epidermal Stem Cell Behavior.” Science 309,1253.
• Ferrón S et al. (2004). “Telomere shortening and chromosomal instability abrogates proliferation of adult but not embryonic neural stem cells.” Development 131(16):4059-70.

Stress

• Wikgren M et al. (2012). “Short telomeres in depression and the general population are associated with a hypocortisolemic state.” Biol Psychiatry. Feb 15;71(4):294-300.
• Babizhayev MA et al. (2011). “Telomere length is a biomarker of cumulative oxidative stress, biologic age, and an independent predictor of survival and therapeutic treatment requirement associated with smoking behavior.” Am J Ther. Nov;18(6):e209-26.
• Sahin E et al. (2010). “Linking functional decline of telomeres, mitochondria and stem cells during ageing.” Nature. Mar 25;464(7288):520-8.
• Glass D et al. (2010). “No correlation between childhood maltreatment and telomere length” Biol Psychiatry. Sep 15;68(6):e21-2; author reply e23-4.
• Kananen L et al. (2010). “Childhood adversities are associated with shorter telomere length at adult age both in individuals with an anxiety disorder and controls.” PLoS One. May 25;5(5):e10826.
• Wolkowitz OM et al. (2010). “Depression gets old fast: do stress and depression accelerate cell aging?” Depress Anxiety. Apr;27(4):327-38.
• Tyrka AR et al. (2010). “Childhood maltreatment and telomere shortening: preliminary support for an effect of early stress on cellular aging.” Biol Psychiatry. Mar 15;67(6):531-4.
• Choi J et al. (2008). “Reduced telomerase activity in human T lymphocytes exposed to cortisol.” Brain Behav Immun. May;22(4):600-5.
• Kurz DJ et al. (2004). “Chronic oxidative stress compromises telomere integrity and accelerates the onset of senescence in human endothelial cells.” J Cell Sci. May 1;117(Pt 11):2417-26.

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